Exploring Pediatric Pathology

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International Neuroblastoma Risk Group Staging System

International Neuroblastoma Risk Group Staging System
L1Localized tumor not involving vital structures as defined by the list of IDRFs and
confined to one body compartment
L2Locoregional tumor with presence of one or more IDRFs
MDistant metastatic disease (except stage MS)
MSMetastatic disease in children younger than 18 months with metastases confined to skin,
liver, and/or bone marrow

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